Telo Therapeutics is developing orally bioavailable next generation inhibitors of nuclear transport, a critical nexus among many cancer cell signaling pathways. The company’s unique chemistry and distinct mechanism of action result in a favorable safety profile and lead to rapid tumor regressions across multiple cancer types including multiple myeloma, brain, liver, lung, bladder, and prostate. Telo has generated durable complete responses with just two weeks of dosing in xenografts of both multiple myeloma and glioblastoma. Telo is uniquely positioned to unlock the full potential of targeting nuclear transport in multiple myeloma tumors and beyond. Telo is actively raising a Series A financing to advance its small molecule to Investigational New Drug (IND) and run a Phase 1 proof-of-concept trial. Telo is targeting first patient dosing in 2H of 2024.